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Cold Sore
Treatments

What helps with cold sores? Cold sore creams, patches and ointments

If you get cold sores, you’ll know how uncomfortable and irritating they can be. While there’s no full cure for the HSV-1 virus behind them, there are plenty of ways to speed up healing and ease the discomfort.

But with an array of cold sore creams, patches or ointments available, which treatment is going to give you the best relief from cold sores?

Remember:

  • Cold sores often start with tingling, itching, or burning
  • They typically heal within 10 days
  • The right products can help relieve symptoms and promote healing

Cold sore creams and ointments

To treat cold sores, antiviral creams and ointments are helpful. Look for ones with phenol or menthol, as they numb the area and relieve tingling and burning. These treatments are available over the counter at your local pharmacy. If you're unsure which to choose, a quick chat with your pharmacist can help.

What to look for in cold sore creams

Not all cold sore creams are the same — different products use different active ingredients.

Some of the most effective options include:

  • Acyclovir cream
  • Penciclovir cream
  • Docosanol cream

These antiviral creams are easy to find at most UK pharmacies. If you're feeling unsure, a quick chat with your pharmacist can help you choose the best one for your needs.

How do creams and ointments help with cold sores?

Cold sore creams work by soothing the skin and helping cold sores heal a little faster. While they don’t get rid of the virus, they can make flare-ups feel less intense. The key is to start using the cream as soon as you feel that first tingle, usually a sign a sore is on the way. Apply it every couple of hours during the day, and you might shave a day or so off the healing time.

Cold sore patches

Cold sore patches are a popular choice because they speed up recovery and make outbreaks easier to manage. They use hydrocolloid technology — a gel-like material that keeps the area moist (helping cold sores heal faster).

What exactly does the Compeed patch® do?

Compeed® cold sore patches have lots of benefits:

  • They speed up healing and reduce scabbing
  • They protect the cold sore from dirt and bacteria, lowering the risk of infection
  • They cover up the sore, making it less visible
  • They reduce the chance of spreading the virus through contact

Can you use cold sore creams and patches together?

Cold sore creams and patches each have their own benefits, but many people wonder if they can be used at the same time. While it’s best not to layer them directly (since a patch won’t stick well over cream), you can use them at different stages of the outbreak.

For example, apply an antiviral cream like acyclovir at the first sign of tingling to slow the virus down. Once the sore forms, switch to the Compeed® patch to protect the area, speed up recovery, and make the sore less noticeable. This flexible approach helps you get the best of both treatments, depending on where you are in the healing process.

Can Compeed® patches be worn overnight?

Yes, you can definitely wear a cold sore patch overnight. In fact, it’s a great way to protect the sore while you sleep. The patch helps shield it from irritation, keeps it moist, and speeds up healing. Just make sure to apply it to clean, dry skin before bed. Then, take it off in the morning and replace it with a fresh patch if needed to keep the healing process going.

Can you use makeup over a cold sore patch?

Yes, you can. The patch creates a smooth surface, which makes it easier to apply foundation, concealer, or other makeup products without irritating the sore. Just make sure the patch is securely in place before applying, and be gentle when blending products to avoid disturbing the patch. Also, try to use non-comedogenic makeup (ones that won't clog pores) to avoid any potential irritation around the cold sore.

Are there any side effects of using cold sore patches?

Cold sore patches are generally safe to use, but like any product, they may cause soreness for some people, especially those with sensitive skin. If you experience redness, itching, or discomfort after using the patch, it’s best to remove it and discontinue use. If symptoms persist, speak to a healthcare professional.

When it comes to treating cold sores, whether you opt for a cream, or a patch depends on what works best for you. For instance, if you’re always on the go, you might not have the time to apply cream as often as needed. On the other hand, if you're concerned about how your cold sore looks, you might prefer a patch to cover it up.

Both treatments help you heal, but a cold sore patch also acts as a protective barrier. It lowers the risk of spreading the virus, prevents infection, and creates a better healing environment.

Sources:

  1. Jaliman, D. Understanding Cold Sores – Treatment. WebMD 2021. https://www.webmd.com/skin-problems-and-treatments/understanding-cold-sores-treatment

  2. Khatri, M. Cold Sores. Web MD. 2021. https://www.webmd.com/skin-problems-and-treatments/understanding-cold-sores-basics

  3. Institute for Quality and Efficiency in Health Care (IQWiG). How effective are creams and tablets for the treatment of cold sores? InformedHealth.org. 2018. https://www.ncbi.nlm.nih.gov/books/NBK525789/

  4. NHS Inform. Cold Sores. NHS. 2021. https://www.nhsinform.scot/illnesses-and-conditions/mouth/cold-sore#treating-cold-sores

  5. Karlsmark T, Goodman JJ, Drouault Y, Lufrano L, Pledger GW, Cold Sore Study Group. Randomized clinical study comparing Compeed cold sore patch to acyclovir cream 5% in the treatment of herpes simplex labialis. J Eur Acad Dermatol Venereol. 2008 Nov; 22(10):1184-92. https://pubmed.ncbi.nlm.nih.gov/18462303

 
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